Skip to main content
Search roles

Manager Health Economics & Payer Evidence ( HEPE)

Location Mississauga, Ontario, Canada Job ID R-237327 Date posted 15/10/2025

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, daring thinking, and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to build a strong culture of collaboration and partnership by engaging face-to-face in our offices 3 days a week. Our head office and BlueSky Hub in downtown Toronto are purposely crafted with collaboration in mind, providing space where teams can come together to strategize, brainstorm, and connect on key projects.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca is an excellent place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking bold actions to address some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.

Reporting to the Director, Payer Evidence, Methods, & Access Affairs (PEMA), you will be accountable for unlocking the value of our medicines through the strategic design and delivery of economic models and payer evidence to HTA agencies and payers in Canada. Using your expertise in health economics and evidence generation, you will lead the creation of economic evidence plans, working with external clinical and payer experts, in Canada and abroad, as well as a diverse cross-functional team to execute and implement your strategies. This includes conducting external literature reviews, exploring public databases, or generating customized real-world evidence to support your health economic modelling. You will provide thought leadership to the Canadian health economic community through publications and presentations. This role will make a difference in the way healthcare is valued and improve the lives of Canadian patients through access to innovative medicines.

Responsibilities

  • You lead the full design, development, and deployment of high-quality economic dossiers to HTA agencies (i.e. CDA-AMC, INESSS) supporting reimbursement submission to the public healthcare system and private insurers, ensuring accurate, strategic, and timely filings for assigned portfolio.
  • You will work with Global colleagues in critically assessing the applicability of health economic models and comparative evidence methods (e.g. NMAs/MAICs), leading adaptations to meet Canadian requirements.
  • You devise plans to demonstrate the value of our products to payers and HTA decision-makers, working with external experts, translating payer evidence into economic value, and supporting publications to benefit the scientific community. You will attend and present at external conferences and meetings.
  • In collaboration with the cross-functional team, you engage with external stakeholders to validate economic evaluation strategies and novel approaches. Through your engagements, you will build a network of external stakeholders (economists, clinicians, academics).
  • You will work with the Director PEMA, to understand, assess, and identify best HTA and health economic practices from other healthcare systems and developing plans on adapting these to the Canadian healthcare environment
  • You will act as the project owner when working with vendors on health economic related projects.

Qualifications/Competencies

  • A genuine interest in health economic evaluation methods, applications, and HTA.
  • Advanced education in a numerate subject (e.g. health economics, epidemiology, biostatistics, healthcare forecasting, management science).
  • 3+ years of pharmaceutical industry or health-related/HTA experience involving reimbursement or health policy, or similar agency/government experience.
  • Practical experience with HTA, cost-effectiveness models, systematic reviews, network meta-analysis, survival/statistical analyses, budget impact models.
  • A thorough understanding of payer evidence requirements (HRQoL studies, costing studies, SLRs, ITCs, retrospective database analyses, prospective physician or patient epidemiological studies) and applications of payer evidence.
  • A strong understanding and interest of healthcare systems and reimbursement processes in Canada and abroad

Skills and Capabilities

  • A high level of initiative, sense of urgency, and ability to lead multiple priorities of significant scope in a fast-paced environment
  • Critical thinking to objectively appraise evidence with detailed, analytical skills in reviewing pharmacoeconomic submission materials
  • Strategically agile with the ability to synthesize information from diverse sources to inform and formulate strategies and initiatives
  • As the future oncology business rapidly changes, this role requires learning flexibility and working with ambiguity is necessary
  • Demonstrated ability to work with cross functional and global teams with excellent communication and project management skills

Great People want to Work with us! Find out why:

This is the place to make a meaningful impact – on patients’ lives and your personal growth. It’s both exciting and inspiring, and it’s what keeps us motivated every day.

Ready to make a difference? Apply now!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com (mailto:AZCHumanResources@astrazeneca.com).

Date Posted

16-Oct-2025

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Join our Talent Network

Be the first to receive job updates and news from AstraZeneca

Sign up
Glassdoor logo Rated four stars on Glassdoor

Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value our people.